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The action of GLP-1 RAs is to enhance insulin synthesis and inhibit glucagon secretion by activating GLP-1 receptors
First few months: This is typically the active titration phase - providers adjusting the dose based on tolerance and response, GI side effects (when present) often diminishing, and more visible weight changes becoming apparent for patients who respond to treatment
Maternally transmitted severe glucose 6 phosphate dehydrogenase deficiency is an embryonic lethal
Reduced glutathione protects
J Am Soc Nephrol 31:21842192
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